Performing radiosynthesis in microvolumes to maximize molar activity of tracers for positron emission tomography
نویسندگان
چکیده
منابع مشابه
Stereospecific radiosynthesis of 3-fluoro amino acids: access to enantiomerically pure radioligands for positron emission tomography.
A variety of substituted non-racemic aziridine-2-carboxylates equivalent to amino acids were prepared and subjected to ring opening reaction by [18F/19F]fluoride. The regio and stereospecific ring opening depends on the substituents on the nitrogen as well as both the carbons of aziridines. The applicability of the methods to afford access to 3-[18F/19F]fluoro amino acids are illustrated.
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ژورنال
عنوان ژورنال: Communications Chemistry
سال: 2018
ISSN: 2399-3669
DOI: 10.1038/s42004-018-0009-z